A part of the functionality of refdb is available through a web interface. This certainly increases the usability for those used to graphical user interfaces, but the functionality is somewhat limited as compared to the command line clients.
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The following operations are available currently:
List available databases and select one for your queries
Retrieve references with either a simple or an advanced query
Edit references
Add new references
Convert BibTeX and Pubmed references to RIS
Remove references
Add and remove references from your personal reference list