refdb was designed to run on as many platforms as possible and has positively been seen running on the following operating systems:
GNU/Linux
FreeBSD
NetBSD
OSX
Solaris
Windows/Cygwin
While this portability excludes fancy GUI bells and whistles, it makes it (most likely) possible to run refdb on the hardware and operating system that you happen to have. Both the clients and the application server should compile on all systems with a decent C compiler like gcc. There should be no problems to run refdb on heterogenous networks. For Windows users the free Cygwin tools are recommended. Cygwin is a POSIX layer on top of Win32 including a useful selection of the popular GNU tools.
To simplify the task of porting refdb to other operating systems the package uses autoconf and automake.